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Editor’s note: Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. With the Omicron variant of the coronavirus blazing across the United States, President Joe Biden offered reassurance on Tuesday to Americans who have followed public health guidance to get vaccinated and boosted, and delivered a stark warning to those who haven’t.
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Doctors should prescribe fewer antidepressants and for shorter periods of time, because of the ongoing uncertainties about their effectiveness and the potential severity and durability of the withdrawal symptoms associated with them, suggests a review of the evidence on antidepressant use, published online in the Drug and Therapeutics Bulletin. The use of antidepressants is also
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In this article DAL Delta Air Lines airplanes at the Hartsfield-Jackson Atlanta International Airport (ATL) in Atlanta, Georgia, U.S., on Tuesday, Dec. 21, 2021. Elijah Nouvelage | Bloomberg | Getty Images Delta Air Lines CEO Ed Bastian on Tuesday asked the Centers for Disease Control and Prevention to halve its recommended quarantine time for people
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In a recent multinational study published on the medRxiv* preprint server, researchers determine the long-term adverse mental health symptoms associated with coronavirus disease (COVID-19) by estimating acute infection severity. Study: Acute COVID-19 severity and 16-month mental morbidity trajectories in patient populations of six nations. Image Credit: Drazen Zigic / Shutterstock.com Significance of post-COVID mental health
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Pairing a novel cytotoxic agent with bevacizumab (Avastin) failed to improve progression-free survival (PFS) versus standard therapy in older patients with metastatic colorectal cancer (mCRC) ineligible for intensive therapy, a randomized trial showed. Investigator-assessed PFS was 9.4 months with trifluridine/tipiracil (Lonsurf) plus bevacizumab and 9.3 months with capecitabine plus the angiogenesis inhibitor. PFS by blinded
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A scoring criterion which can distinguish between benign and malignant tumors in pediatric patients with renal masses could help determine if they can benefit from partial rather than radical nephrectomy (removal of the kidney), according to new study findings. The RENAL nephrometry score is widely used in cases of adult kidney cancer to determine who
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There’s a sort-of unspoken, but widely acknowledged, ‘life path’ we’re all expected to follow – but none of our journeys are exactly the same. Here, we’re exploring the mental health impact of deviating from the predicted ‘life milestones’ course, and how to handle it The word ‘milestone’ is said to date back to the third
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The Food and Drug Administration has announced that women no longer will have to pick up the abortion pill mifepristone (Mifeprex) in person at certain certified sites and can get a prescription via an online consultation and delivery through the mail. In April 2021, the FDA lifted the in-person dispensing requirement for mifepristone for the duration of the
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The protein UBR7 acts as a histone chaperone, regulating histone re-deposition at specific sites during DNA replication, according a recent study published in The EMBO Journal. This protein was previously identified to regulate nucleotide metabolism, making UBR7 among the first proteins known to affect both processes, according to Daniel Foltz, PhD, associate professor of Biochemistry
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The FDA approved the only biologic for severe asthma without any phenotype or biomarker limitations, manufacturers AstraZeneca and Amgen announced Friday. The first-in-class biologic tezepelumab-ekko (Tezspire) is indicated as an add-on maintenance treatment for patients ages 12 and older with severe asthma. It is not intended for acute bronchospasm or status asthmaticus. As a first-in-class
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I think we thought we saw this coming. And I think we tried to warn everybody. Approaching 2 years into the pandemic, with hundreds of thousands of lives lost and millions sickened, it feels like we’re no closer to an effective public health system prepared to handle what comes next, instead of reacting to things
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