Clinical Trials & Research

Humans have evolved as social animals. From childhood, we are taught the benefits of forging ties and being empathetic as a strategy for survival and mental well-being — or at least that is the ideal. Sometimes, though, such ties morph into the fabric of tribalism, subjecting certain individuals to discriminatory behavior or attitudes. Now, a
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Colorectal, pancreatic, esophageal and stomach cancers-;some of the deadliest kinds of cancer-; have high recurrence rates where the cancer comes back even after successful surgery or radiation treatment. To combat these treatment-resistant cancers, Thomas University Jefferson researchers led by Adam Snook, PhD, an associate professor of pharmacology and experimental therapeutics, instead use what are, in
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Porvair Sciences announce eGecko² – an automated barcode application system that provides the ideal high throughput solution for precisely applying barcode labels onto racks of plates and Petri dishes. Image Credit: Porvair Sciences Limited Based upon a robust and proven label printer and print engine, the eGecko² is a completely integrated printer and application unit in
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Some people who experience heart failure have less biodiversity in their gut or have elevated gut metabolites, both of which are associated with more hospital visits and greater risk of death, according to a systematic review of research findings led by Georgetown University School of Nursing & Health Study researchers and colleagues. The gut microbiome
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A new perspective by researchers from the American Cancer Society (ACS) and the University of Texas Health Science Center at San Antonio shows the high burden of breast cancer mortality in African American (Black) women versus White women began in the United States in the 1980’s. At that time, breast cancer screening (mammography) and treatments
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Mathematical modeling-; which combines math, statistics, computing and data-; is a critical tool for public health professionals, who use it to study how diseases spread, predict the future course of outbreaks and evaluate strategies for controlling epidemics. As the COVID-19 pandemic drove public health decision-making nationwide, a wide range of disease models proliferated. Across the
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Corinne Rovetti is worried about what will happen to the Knoxville Center for Reproductive Health if the Supreme Court overturns the constitutional right to abortion. The clinic, where she has worked for 33 years helping people across a four-state region, could close. “We’re unsure if we’ll be able to maintain services at all,” said Rovetti,
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In a recent study published in Science, researchers found that immune-boosting by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant is contingent on prior coronavirus disease 2019 (COVID-19) history. Study: Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure. Image Credit: CROCOTHERY/Shutterstock The SARS-CoV-2 Omicron variant, which emerged in late 2021, exhibited high
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In a recent study published in The Lancet Rheumatology, researchers assessed the risk of severe coronavirus disease 2019 (COVID-19) in adults with immune-mediated inflammatory diseases and those on immunomodulatory therapies. Study: Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune-modifying therapies: a nationwide cohort study in the OpenSAFELY platform. Image Credit: Zay
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A mass survey of citizens aged 50 to 89 years examined whether cognitive decline could be detected by sagittal spinal balance measurement based on a radiological approach. Doctors from Shinshu University observed associations of sagittal vertical axis (SVA) anteriorization and higher age with lower cognitive function. The sagittal vertical axis is the length of a
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How do cancer cells differ from healthy cells? A new machine learning algorithm called “ikarus” knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal Genome Biology. The AI program has found a gene signature characteristic of tumors. When it comes to identifying patterns in mountains of data, human beings
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Legalizing marijuana in several places worldwide has warranted a lower risk of harm to users. However, there is not sufficient evidence to understand the effect of marijuana when used by pregnant women.    Study: Implications and quantifications of marijuana use regarding neonatal outcomes. Image Credit: Tomsickova Tatyana/Shutterstock In a recent study published in Phytomedicine Plus, researchers
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In a recent study published in Human Reproduction, researchers evaluated the risk of attention-deficit hyperactivity disorder (ADHD) in offspring of infertile mothers or those receiving infertility treatment compared to offspring of mothers with unaided conception. Study: Attention-deficit hyperactivity disorder in children born to mothers with infertility: a population-based cohort study. Image Credit: ClareM/Shutterstock Studies investigating
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In a recent review posted to the OSF* preprint server, the author explained the causes of the mysterious origin of the recent monkeypox outbreaks in non-endemic nations outside Africa. Study: The origin of the mysterious multi-country monkeypox outbreak in non-endemic countries. Image Credit: FOTOGRIN/Shutterstock Background Monkeypox cases are on the rise in several non-endemic nations
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